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Symposium #121 on

Deciphering molecular complexity from protein functions to cellular network in December 15-16, 2015

Let the system speak for itself

PROGRAM

Workshop dates and venue

Our symposium sessions will be held in the Hawaii Convention Center. http://www.meethawaii.com/hawaii-convention-center.aspx

Click Here to see a Google Map of where the technical sessions are located within the Pacifichem 2015 properties along Waikiki Beach and where all of the Topic Areas are located within each property.

The Pacifichem 2015 meeting will start on Tuesday Morning, December 15, 2015 and conclude on Sunday Morning, December 20, 2015.

 
Tue 12/15
Wed 12/16
Morning
8:00-8:05, Opening Remarks  
8:05-8:40, R. Stephen Berry
Finding the macro-micro boundary
8:00-8:35, Martin Gruebele (cancelled)
Protein-RNA interactions in the living cell
8:40-9:10, Ray Luo
A multi-scale method for dynamics simulations of biomolecular systems
8:35-9:05, Dongping Zhong
Dynamics and mechanism of UV-perception by UVR8 Photoreceptor
9:10-9:40, Satoshi Takahashi
Complex folding transition of the B domain of protein A investigated by the high-speed measurement of single-molecule FRET time series
9:05-9:20, James Taylor
Data-driven quantification of heterogeneous microenvironments in live-cell Raman microscopic images
9:40-9:55, coffee break 9:20-9:35, coffee break
9:55-10:30, Hiroyuki Noji
Robustness of rotary catalysis of F1-ATPase rotary motor tested by creating an artifical rotary motor molecule
9:35-10:10, Shoji Takada
Structural insights into chromatin folding and transcriptional regulation
10:30-11:00, Jianshu Cao
Conformational Fluctuations in DNAs and Enzymes
10:10-10:40, Kazuhiro Maeshima
Human genome organization and dynamics: Local nucleosome dynamics facilitate chromatin accessibility
11:00-11:15, David Jacobson
Single-molecule method for counting ligands associated with a conformational transition: Linking ion uptake to nucleic acid folding
10:40-11:10, Jianlan Wu
Beyond Forster resonant energy transfer theory
Lunch
 
Afternoon
13:00-13:35, Bin Zhang (with Peter Wolynes)
Energy landscape theory: from folding proteins to folding chromosomes
13:00-13:35, Herbert Levine
The genetic network underlying the Epithelial-Mesenchymal Transition (EMT)
13:35-14:05, Steve Presse
Enzymes stepping on landmines
13:35-14:05, Xue-Fei LI (with Lei-Han Tang)
Acetate overflow: optimal proteome partitioning and regulation
14:05-14:35, Jianpeng Ma (cancelled)
Enhanced sampling and applications in protein folding in explicit solvent
14:05-14:35, Yi Jiang
Let there be force: Modeling cell-ECM interactions in cancer invasion
14:35-14:50, coffee break 14:35-14:50, coffee break
14:50-15:25, Masaki Sasai
Dynamical energy landscape perspective on protein functioning
14:50-15:25, Ryan Cheng (with Jose Onuchic)
Decision making at the cell level: from bacteria to possibly cancer
15:25-15:55, Tamiki Komatsuzaki
Energy landscapes and conformation network learned from single molecule time series
15:25-15:40, Felipe Herrera
Single-molecule imaging for systems biology via quantum metrology
15:55-16:25, Haw Yang
Modes of protein large-amplitude conformational change from single-molecule experiments
15:40-16:10, Andre Levechenko (cancelled)
Pathways and networks: unraveling the complex organization of signaling networks
16:25-16:40, Vladimir Privman (cancelled)
Signal and information processing with biomolecules: enzyme-catalyzed reactions and their cascades
16:10-16:40, Jin Wang
Landscape and Fluxes of Neural Networks
  16:40-16:45, Closing Remarks