Telluride Workshop on
The Complexity of Dynamics and Kinetics in Many Dimensions

From Braidal Veil Trail in Telluride.  They are winding, aperiodic
but yet somewhat ordered (for a certain temporal period) to the goal,
reminiscent of what functions are in complex systems.

June 20-June 24 2011
Telluride Intermediate School
Telluride Summer Research Center
Telluride, CO, USA


This workshop focuses on the complexity of dynamics and kinetics in complex systems, such as proteins, in terms of the underlying multidimensional energy landscape, the network structure in the conformational, or, in general, state space, and various mathematical models of nature. We aim at having an interdisciplinary meeting that brings both theoretical and experimental researchers together from different fields including time series analysis, energy landscape, statistical physics, network analysis, and single molecule experiments.

This year, the main questions to be addressed are:
1. What are the current and next generation experimental advances to probe the dynamics and kinetics of complex biophysical systems, such as single molecule spectroscopy and microscopy, cell imaging, multi-parameter measurements, and what are the desired analysis methods to scrutinize the observed data?
2. What are the appropriate mathematical languages to model complex dynamics and kinetics from experiments or computer simulations, such as generalized Langevin equations, master equations, networks, disconnectivity graphs? How can the mathematical models be constructed from scalar, multivariate or imaging (spatiotemporal) data? For example, how to extract hidden dimensions, how to reduce dimensions?
3. What are the dynamical and thermodynamical signatures of the constructed models? The related subjects are, for example, diffusion properties, memory effects, the quantification of multiple pathways on the energy landscape and its relations to the protein structures, equilibrium and nonequilibrium properties.
4. If the constructed models are complicated, e.g. in the conformational-space network, how can the essential features be extracted and represented, such as coarse-grained models, quantifying the large scale structure of networks, identifying reaction coordinates and flux?

This Telluride workshop is different from a traditional conference. This workshop is aimed at exploring the new, exciting, open questions, by stirring different disciplines working on different subjects and fields rather than solely to learn about all the wonderful things the participants have already done. Some of the most interesting Telluride workshops have used a format in which the first day or the half of the first day is devoted to setting an agenda of the open topics to be discussed, choosing who should be the formal presenter of each of those topics, and setting the day for each presentation. The material that would, in a traditional conference be presented in a talk, would have been contained in the pre-circulated papers. Then everyone will know the substance of where each subject stands and the focus can be on what needs to be investigated next, and how those things could be approached. We plan to follow this pattern, and will ask the participants to submit one or two papers that they would like the others to see, and to send us a list of the exciting, important open problems that they feel should be discussed at this workshop.

name affiliation
Berry, R. Stephen The University of Chicago,USA
Blank, Kerstin Radboud University Nijmegen,The Netherlands
Chu, Jhih-Wei Uiversity of California, Berkeley,USA,
Hernandez, Rigoberto Georgia Institute of Technology,USA
Kamagata, Kiyoto Tohoku University,Japan
Kawai, Shinnosuke Hokkaido University,Japan
Komatsuzaki, Tamiki Hokkaido University,Japan
Li, Chun Biu Hokkaido University,Japan
Nerukh, Dmitry Aston University,UK
Pearson, John Los Alamos National Laboratory,USA
Terentyeva, Tatyana Katholieke Universiteit Leuven,Belgium
Wang, Jin Stony Brook University,USA
Wu, Jianlan Zhejiang University,China
Yang, Haw Princeton University,USA

Workshop dates and venue
1. Our Telluride workshop "The Complexity of Dynamics and Kinetics in Many Dimensions" will begin on 6/20/2011 (Mon) and will be held at the Telluride Intermediate School. Directions to the workshop location can be found at
2. Breakfast will be served everyday starting from 7:30am at the school and the workshop will start from 8:30am.

Time Table

Mon 6/20 Tue 6/21 Wed 6/22 Thu 6/23 Fri 6/24
7:30 Breakfast served at school from 7:30
8:30 Opening Remark, Set up Agenda Talk and Discussion (each talk ~30 min) (Yang, Chu, Li, Nerukh) SM experiment, modeling and dynamics Talk and Discussion (each talk ~30 min) (Kamagata, Pearson, Vanden-Eijnden,Brujic) SM experiment, modeling and dynamics Talk and Discussion (each talk ~30 min) (Blank, Terentyeva, Kawai, Hernandez) SM experiment, Generalized Langevin dynamics Open Discussion
9:00 Talk and Discussion (each talk ~30 min) (Berry, Komatsuzaki, Wang, Wu) Energy landscape, many dimensional kinetics
11:00 Closing remarks
12:00 (Lunch) in school (Lunch) (Lunch) (Lunch)
13:30 Talk and Discussion (free to be changed) Talk and Discussion (free to be changed) Talk and Discussion (free to be changed) Talk and Discussion (free to be changed)
18:00 Dinner at La Marmotte TSRC Town Talk at Palm Theatre in Telluride High School Reception at Staff House Thursday Night Picnic

Circulation (See Preprints/reprints)

One can register the workshop via the following web page:
(This registration fee is for running our conference at Telluride Science Research Center (TSRC), including using computational facilities and breakfast (a huge variety including hard boiled eggs, ham, bread, pastries, bagels, cheese, juice, coffee, tea) during the workshop)

Telluride Tips & Frequently Asked Questions
please visit here and the travel tips page provided by Douglas J. Tobias .


Tamiki Komatsuzaki
Molecule & Life Nonlinear Sciences Laboratory
Research Institute for Electronic Science
Hokkaido University
TEL&FAX +81(11) 706-9434

Chun-Biu Li
Molecule & Life Nonlinear Sciences Laboratory
Research Institute for Electronic Science
Hokkaido University
TEL&FAX +81(11) 706-9435

R. Stephen Berry
Department of Chemistry, and the James-Franck Institute,
University of Chicago, USA
TEL +1-773-702-7021 FAX:+1-773-702-0805